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Volume 11 - Number 20
Wednesday June 3, 2009


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tip1.gif   Quitting Smoking Improves Lung Function

For smokers with asthma, quitting smoking can improve lung function test scores by more than 15 percent in less than two months.

The findings appear in the second issue for July 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Neil C. Thomson, M.D., of the Departments of Respiratory Medicine and Immunology at the University of Glasgow, and seven associates studied 11 asthmatics who continued to smoke and 10 who quit for six weeks. After only one week of no cigarettes, the researchers said that the lung function test results of the non-smoking patients had improved to a "considerable degree."

"The improvement in lung function seen after smoking cessation was clinically significant," said Dr. Thomson. "It demonstrates that there is a reversible component to the harmful effects of smoking on the airways in asthma."

"The degree of improvement noted for smoking cessation far exceeds that of high-dose anti-inflammatory treatment, such as oral prednisolone, 40 mg daily for 2 weeks, which had no effect on lung function in smokers in our current study and in our previous work," he continued. "The improvement could be due to the removal of the acute bronchoconstrictor effects of cigarette smoke or a reduction in the proinflammatory effects of cigarette smoke on the airways."

In addition to the improved lung function test scores, the "quit" group also showed a reduction in sputum neutrophil counts when compared to those of smokers. Neutrophils are white blood cells (phagocytes) that engulf bacterial and fungal infections, along with ingesting foreign debris.

"Sputum neutrophil counts are reported to be increased in heavy smokers with asthma compared with nonsmokers with asthma," said Dr. Thomson.

The authors noted that in many developed countries, more than 20 percent of adults with asthma are active smokers, with particularly high rates of acute asthmatics visiting hospital emergency rooms.

The smokers with asthma recruited for this study were aged 18 to 60 and had lung function score results of less than 85 percent of their predicted level. They all had a cigarette history of over 10-pack-years and smoked more than 10 cigarettes a day. The investigators saw no differences in the baseline physiological characteristics between the smoking group and those who quit.

Of the 10 subjects who successfully stopped smoking and completed the six-week study, five used nicotine patches, one employed acupuncture and four quit without any aid. The researchers believe that their findings highlight the importance of smoking cessation for adults with asthma.

Contact:

Neil C. Thomson, M.D., Department of Respiratory Medicine, Division of Immunology, Infection, and Inflammation, University of Glasgow and Western Infirmary, Glasgow G11 6NT, United KingdomPhone: + 44 141 211 3240E-mail: n.c.thomson@clinmed.gla.ac.uk

tip2.gif (1572 bytes)  I Feel 100% Better Since I Quit Smoking

"Not smoking makes me feel great!" Often you will hear an ex-smoker excitingly express this statement when first quitting cigarettes. What is amazing is when you think back to the days when the very same smoker would blatantly proclaim that his smoking never caused him any difficulty. He functioned perfectly normal for someone his age. It is impossible for any smoker to accurately judge just how much impairment his smoking is causing. Not until he stops will he actually recognize the full degree of improvements possible by quitting smoking.

The statement that not smoking makes the ex-smoker feel great is very misleading. Not smoking doesn't make people feel great. It actually only makes them feel normal. If a person who never smoked a day in his life decides one morning not to have a cigarette, he will not feel any better or worse than the morning before. But if a person wakes up everyday and smokes a cigarette, followed by 20, 40, 60 or more before going back to bed, he will feel the effects of nicotine dependence. He never feels normal. His life consists of a chronic withdrawal state, only alleviated by lighting one cigarette every 20 to 30 minutes.

While smoking in these intervals keeps the suffering of withdrawal down to a minimum, it does so at a cost. It impairs his breathing, circulation, elevates his carbon monoxide levels, wipes out his cilia, robs his strength and endurance, and greatly increases his risks of deadly diseases like cancer. All this will cost him hundreds of dollars a year, make him appear socially ostracized, and even viewed by family and friends as weak or unintelligent. It is no wonder that once he quits smoking he feels so much better. But it is important for the ex-smoker to realize that he feels so much better because smoking made him feel so bad.

For once a smoker quits, he often forgets just how rotten life was as a smoker. He forgets the bad cigarettes, the cough, the aches and pains, the dirty looks, the inconveniences, and most importantly, the addiction. He forgets what life was truly like as a smoker. Unfortunately, he doesn't forget everything. One thought often remains, lingering for years and even decades--the thought of the best cigarette he ever smoked. It may be a cigarette he smoked 20 years earlier, but it is the one he remembers above all others. Without keeping an accurate perspective of what life was really like with cigarettes, the thought of the best cigarette often leads to an attempt to recapture the bliss by taking a puff. What follows is an unexpected and worse, an unwanted relapse to a full fledge addiction.

To stay off cigarettes, some people look at smoking in an artificially negative light. They think of the worst condition smoking may or may not really cause them. Don't look at cigarettes this way. But on the same note, don't look at cigarettes in an artificially positive light either. Don't think of smoking as being inhaling one or two delightful cigarettes a day just when you feel like it. You couldn't do that before and you will never do it that way again. Rather, look at smoking as it actually was. It was expensive, inconvenient, and sociably unacceptable on a daily basis. It controlled you totally. It was costing you your health and had the full potential of one day costing your life. See cigarettes for what they were. If you remember your life as a smoker it will be easy to NEVER TAKE ANOTHER PUFF!

© Joel Spitzer 1988, 2000

 

tip3.gif  What Does Nicotine Do to Your Body?

Nicotine, the active and addictive ingredient of tobacco, is a mild central nervous system stimulant and a stronger cardiovascular system stimulant. It constricts blood vessels, increasing the blood pressure and stimulating the heart, and raises the blood fat levels. In its liquid form, nicotine is a powerful poison-the injection of even one drop would be deadly. It is the nicotine, not the smoke, that causes people to continue to smoke cigarettes, but it is the cigarette smoke that causes many of the problems.

Cigarette smoke is a combination of lethal gases-carbon monoxide, hydrogen cyanide, and nitrogen and sulphur oxides-and tars, which contain an estimated 4,000 chemicals. Some of these chemical agents are introduced by current tobacco manufacturing processes. Although tobacco has been smoked for centuries, only recently has it moved from the naturally grown and dried process. It appears that in the last century the negative effects of smoking have skyrocketed. My belief, which is shared by many authorities, is that much of the added risk is produced by the chemical treatment and unnatural processing of tobacco. The little research that has been done on this (it is not sponsored by the industry) suggests that natural tobacco poses much less cancer risk, as well as cardiovascular disease risk, though this is predominately from the nicotine, which is not changed by processing.

Dangers in modern tobacco products include pesticides used during growth and chemicals added to the tobacco to make it burn better or taste different. Chemicals added to the leaves and papers to enhance burning are among the major causes of fire deaths in this country, as cigarettes continue to burn after they have been put down. The forced burning also makes people smoke more of each cigarette in order to complete it. Sugar curing and rapid flue drying are also associated with increased toxicity of cigarettes. Kerosene heat drying contaminates the tobacco with another toxic hydrocarbon. Using a natural tobacco, such as some imported from France or Germany and a few U.S.-made cigarettes (possibly Shermans and More), may reduce the smoking risk. If a cigarette does not go out when left alone, it has been chemically treated.

Other toxic contaminants in cigarettes include cadmium (which affects the kidneys, arteries, and blood pressure), lead, arsenic, cyanide, and nickel. Dioxin, the most toxic pesticide chemical known to date, has been found in cigarettes. Acetonitrile, another pesticide, is also found in tobacco. The nitrogen gases from cigarettes generate carcinogenic nitrosamines in the body tissues. The tars in smoke contain polynuclear aromatic hydrocarbons (PAH), carcinogenic materials that bind with cellular DNA to cause damage. Antioxidant therapy, particularly with vitamin C, is protective against both PAH and nitrosamines, and extra C also blocks the irritating effects of smoke. Smoking itself reduces vitamin C absorption; blood levels of ascorbic acid average about 30-40 percent lower in smokers than in non-smokers.

Radioactive materials are also found in cigarette smoke; polonium is the most common. Some authorities believe that cigarettes are our greatest source of radiation. A smoker of one and a half packs per day may be exposed to radiation equal to 300 chest x-rays a year. Radiation is a strong aging factor. Acetaldehyde, a chemical released during smoking, causes aging, especially of the skin, as it affects the cross-linking bonds that hold our tissues together.

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